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7-ethyl-10-hydroxycamptothecin




Synonyms: 7-ethyl-10-hydro(20)s-camptothecin ; SN38
CAS No.:86639-52-3
Brief introduction: 7-ethyl-10-hydroxycamptothecin's another name is SN38.SN38 can make topoisomerase _¢ñinactive,lead DNA to irreversible single chain break, cell death and have no crossed medicine-resistant with 5_Fu,Cisplatin.
Formula:


Molecular weight: 392.34
Structure:


Property: buff crystal powder. melting point:230~237¡æ
Quality Standard:
Inspection itemSpecification
AppearanceLight yellow Crystal Powder
IdentificationPositive
Melting point230-237¡æ
Loss on drying1.0%
SolubilityClear yellow solution at 1mg Plus 1ml of dimethyl sulfoxide
Heavy metals£¼20ppm
Proton NMR SpectrumConsistent with structure
Sulphated ash0.1%
Content(HPLC)98%
Total plate count£¼1000cfu/g
Mould£¼100cfu/g
E.ColiNEG
SalmonellaNEG